The journey to unlocking the secrets to younger-looking skin has started since the dawn of civilisation. Even in ancient civilisations, they have explored and tried several natural components believed to give them their desired youthful glow – from milk to body waste matter and even blood!
Fortunately, technology has since advanced to the point where we no longer need to depend on ineffectual and sometimes, toxic, substances. We may not have attained the fountain of youth, but there are numerous effective yet safe ways to reduce severe signs of ageing.
Introduction To Photoaging
Let’s get one thing out of the way first: the ageing process is not only natural, but inevitable. It results from the impact of the accumulation of molecular and cellular damage over time. There is no sure way to effectively be rid of all signs of this natural biological phenomenon.
Skin ageing can be divided into two basic processes: intrinsic ageing and photoaging.
Intrinsic ageing is a genetically determined process that is affected by degenerative effects of hormonal shifts, free radicals and the body’s inability to repair skin damage. Skin that displays signs of intrinsic ageing is smooth, pale and will feature fine wrinkles.
Extrinsic ageing, on the other hand, describes premature skin ageing in chronically photodamaged skin. It’s a result of lifestyle and environmental factors, mostly from prolonged exposure to the sun. Characteristics of severe photodamage skin include severe wrinkling and pigmentary changes, such as mottled pigmentation and solar lentigo.
Ultraviolet Light: The Main Culprit Of Photodamaged Skin
It’s a very well-known fact that the sun, specifically its ultraviolet (UV) rays, poses long-term, adverse consequences on the skin, particularly to the skin’s DNA. DNA is a very large molecule that will typically absorb the energy it gains when hit with a UV photon, before it quickly releases that energy as heat. Since the DNA is extremely competent at what it does, the damage sustained is typically less than 0.1% of the time – that is, if the sun exposure is done in moderation.
Suppose moderation is not practised; continued exposure to UV radiation can overwhelm the body’s defences. It can result in the structural rearrangement of nucleotides that will then lead to defects in the DNA strand.
Moreover, UV radiation has enough energy to cause ionisation, a process in which electrons break away from atoms. This results in a drastic change in the chemical properties of atoms, causing them to uncharacteristically form or break chemical bonds, which can be highly damaging to materials and living tissues.
Stem Cells: Rendering Its Abilities To Moot
Adult tissues, including the skin epidermis, have a high rate of cell turnover. This is thanks to stem cells’ ability to self-renew and differentiate into different cell lineages. As the body’s very own raw materials, stem cells and their ability for self-renewal is crucial to the maintenance of tissue homeostasis. This, along with their innate high resistance to DNA damage and highly active DNA repair mechanisms, allows cells and tissues to renew and repair themselves.
However, as with many other biological components, stem cells can be impaired in advanced age and are vulnerable to repetitive exposure to UV rays. If they are exposed to UV rays for a prolonged period, it may lead to a decrease in colony-forming potential and viability of skin stem cells, and dysfunctional DNA repair mechanisms. This means stem cells cannot replace or repair any deformed or mutated DNA genes, even if the body requires them to. The maintenance of existing skin cells and tissues will be affected, thus kickstarting the premature ageing process.
As such, photodamage not only develops into several complications (both on the epidermis and molecular levels), but finding ways to heal from its effects becomes just as complicated.
Saying Goodbye To Photoaging Skin
Unfortunately, there is still no cure to help treat photoaging completely. There are, however, treatments that can help improve the appearance of photoaging skin.
1. Topical Medication
Certain medications such as topical retinoid medication can help to reduce the appearance of hyperpigmentation and even out your skin tone. These topical medications can also address roughness and fine lines caused by photoaging.
2. Chemical Peels
A chemical peel helps remove several layers of sun-damaged skin cells, leaving skin with a more even surface and colour. Moreover, it may also stimulate collagen production, which will effectively improve the skin’s texture and elasticity.
The dermatologist will first thoroughly clean the face before applying the peeling agent. After several minutes, the peel is then neutralised to reduce the burning sensation and remove the chemical solution. You can expect mild facial redness and occasional swelling for the next 48 hours.
3. Photodynamic Therapy
Photodynamic therapy utilises wavelengths of monochromatic light to stimulate specific cells within the body. This helps to reduce the appearance of lesions caused by photodamage such as actinic keratosis and even early forms of skin cancer.
Omnilux phototherapy for example, can be used to activate photosensitising agents to create a photochemical reaction that selectively destroys cancer cells. Photosensitising agents are drugs that are typically administered topically and are usually concentrated in abnormal cells. These agents become active when light of a certain wavelength is directed onto the area, and it is the photodynamic reaction between the photosensitising agent, light and oxygen that kills these abnormal cells in precancerous spots that result from prolonged sun exposure.
4. Aesthetic Lasers
Aesthetic lasers deliver laser light energy directly to the skin tissue, creating a “photoacoustic” impact, breaking up the pigmentation into particles that can be easily eliminated via your body’s natural waste-disposal system.
Since photoaging skin results from damaged skin cells and tissues, treatments that help stimulate the rebuilding and restructuring of the dermis are the best way to treat the long-term effects of photodamage.
PicoWay Resolve
The PicoWay Resolve Fractional Resurfacing is the first and only laser with ground-breaking holographic fractional technology, effectively delivering predictable energy with uniform treatment.
The PicoWay Resolve delivers consistent and precise laser energy of 532nm wavelength and 1064nm wavelength to treat shallow and deeper lesions, respectively. These beamlets will reach below the skin’s surface, causing a photoacoustic effect. The tiny open spaces left from the treatment are then filled with the growth of new collagen and elastin. With just one or two sessions, you can expect to see visible improvements to skin tone, texture and wrinkles.
PicoSure Focus
Also known as Focused Lens Array (FOCUSTM), PicoSure Focus utilises a diffractive lens array handpiece capable of delivering 755nm wavelength beamlets as apexes of high-fluence regions surrounding by low-fluence regions. This means only 10% of the tissue is exposed to ultra-high-fluence, ensuring little to no thermal injury to the surrounding tissue.
Pico laser treatments have become a pervasive treatment in the cosmetic industry – and it’s easy to see why. Not only are they effective, but they are also non-invasive. Pico laser technology also poses no side-effects, which translates to negligible downtime rejuvenation. Moreover, its skin treatment palette extends from lightest to darkest skin tones, so those with melanin can also enjoy youthful-looking skin!
Final Thoughts
Since there is no true cure for photoaging, the best thing to do is to simply slather good sun protection to prevent it from happening in the first place! However, even a sunscreen with SPF 50 PA+++ will not give you 100% protection from those harmful UV rays.
At Angeline Yong Dermatology, we fully understand and care for those whose self-esteem has taken a hit from photodamaged skin. As such, we continuously strive to deliver tailored solutions that can treat your skin issues, leaving you with radiant and healthier skin.
Apart from being an experienced dermatologist in Singapore, Dr Yong is also a highly-esteemed opinion leader in several aesthetic dermatology products and laser devices – including the PicoSure laser. She is also appointed as a key opinion leader for Cynosure in the Asia Pacific region.
Ageing gracefully has never been easier! Let us help you feel more comfortable in your own skin. Contact us at AYD to book a consultation with Dr Yong.
References
Panich, U., Sittithumcharee, G., Rathviboon, N., & Jirawatnotai, S. (2016). Ultraviolet radiation-induced skin aging: the role of DNA damage and oxidative stress in epidermal stem cell damage mediated skin aging. Stem cells international, 2016.
Chung, J. H. (2003). Photoaging in asians. Photodermatology, photoimmunology & photomedicine, 19(3), 109-121.